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Anti -Fibrin Degradation Product, D-Dimer
Anti -Fibrin Degradation Product, D-Dimer
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| Human D-dimer (DD), a specific degradation product of cross-linked fibrin, is released into the bloodstream during clot breakdown. It is used as an indicator of blood clots, venous thromboses or pulmonary embolisms. | | | Catalog # | F4197-19 | | Applications | Suitable for use in ELISA and Western Blot. Other applications have not been tested. | | Recommended Dilution | Sandwich ELISA: Plasma samples should be diluted with 10mM Tris-HCl buffer, pH 7.5, 1M sodium chloride, 0.1% Tween 20. To avoid non-specific binding, the final sodium chloride concentration in plasma samples should be 0.5M. | | Optimal dilutions to be determined by the researcher. | | Recommended Pair | Suitable for use as the capture or solid phase antibody. | | Matched to F4197-17, F4197-18 or F4197-20 as the detection or conjugate (label) antibody. | | Hydridoma | Sp2/0 myeloma cells with spleen cells from Balb/c mice. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 1.B.673 | | Host | Mouse | | Source | Human | | Concentration | ~10mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide. | | Purity | Purified by Protein A affinity chromatography (>90% SDS-PAGE). | | Immunogen | Homogenized fibrin clot | | Specificity | Recognizes human D-dimer (DD), a specific degradation product of cross-linked fibrin, and high molecular weight fibrin degradation products. No crossreaction with D-monomer. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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