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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified E

Thrombin converts fibrinogen into fibrin, which is then cross-linked by factor XIII to form a blood clot. Also recognises fibrin degradation products (FDPs), substances that are left behind after a blood clot dissolves. This process, called fibrinolysis, is produced by the action of enzymes such as plasmin on fibrin. One FDP is D-dimer, levels of which can be used to diagnose deep vein thrombosis or pulmonary embolism. fibrinolytic system is also closely linked to the control of inflammation.
Catalog #	F4200-04D
Applications	Suitable for use in ELISA. Other applications not tested.
Recommended Dilution	Optimal dilutions to be determined by the researcher.
Hybridoma	Spleen cells from immunized Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	9A168
Host	Mouse
Source	Human
Concentration	~1mg/ml
Form	Supplied as a liquid in PBS, pH7.4, 0.09% sodium azide.
Purity	Purified by Protein A affinity chromatography.
Immunogen	Fibrin degradation products.
Specificity	Recognizes human fibrinogen, a glycoprotein produced in the liver. Fibrinogen is a hexamer, consisting of two sets of three subunits (alpha, beta and gamma).
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.