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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Fibrinogen (Coagulation Factor I)

Anti -Fibrinogen (Coagulation Factor I)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Thrombin converts fibrinogen into fibrin, which is then cross-linked by factor XIII to form a blood clot. Also recognises fibrin degradation products (FDPs), substances that are left behind after a blood clot dissolves. This process, called fibrinolysis, is produced by the action of enzymes such as plasmin on fibrin. One FDP is D-dimer, levels of which can be used to diagnose deep vein thrombosis or pulmonary embolism. fibrinolytic system is also closely linked to the control of inflammation.
Catalog #F4200-04D
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaSpleen cells from immunized Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9A168
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH7.4, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenFibrin degradation products.
SpecificityRecognizes human fibrinogen, a glycoprotein produced in the liver. Fibrinogen is a hexamer, consisting of two sets of three subunits (alpha, beta and gamma).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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