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You are here:Home » Growth Factors, Cytokines » Growth Factors-FGF » Fibroblast Growth Factor, Acidic, Recombinant, Human (FGF Acidic, FGFa, aFGF, FGF alpha, Fibroblast Growth Factor 1, FGF1, AFGF, Beta Endothelial Cell Growth Factor alpha, ECGFA, Endothelial Cell Growth Factor beta, ECGF-beta, ECGFB, ECGF, GLIO703, Hepari

Fibroblast Growth Factor, Acidic, Recombinant, Human (FGF Acidic, FGFa, aFGF, FGF alpha,
Fibroblast Growth Factor 1, FGF1, AFGF, Beta Endothelial Cell Growth Factor alpha, ECGFA,
Endothelial Cell Growth Factor beta, ECGF-beta, ECGFB, ECGF, GLIO703, Hepari

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Specifications

Human FGF acidic, also known as FGF 1 (fibroblast growth factor 1), is a member of the heparin-binding growth factor family, widely distributed in the peripheral and central nervous systems.
Catalog #F4210-01H
FGF 1 acts as a potent neurotrophic factor, playing a key role during prenatal development and postnatal growth/regeneration and is dependent upon interactions with heparin sulfate (HS) proteoglycans located on cell surfaces and in the extracellular matrix, and the four high affinity tyrosine kinase receptors, designated FGFR-1,-2,-3 and -4.
Bioactivity was determined by the dose-dependent stimulation of thymidine uptake by FGF receptor-expressing BaF3 cells. The ED50 is <10ng/ml.
SourceRecombinant corresponding to human FGF acidic, expressed in E. coli.
Molecular Weight~15.8 kD (140aa Sequence)
Activity1 x 105 units/mg
Endotoxin 0.1 ng/ug
ApplicationsSuitable for use in Functional Assays. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with 50ul of 5mM sodium phosphate, pH 8.0. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceHuman
PurityPurified: ~95% (SDS PAGE, HPLC)
FormSupplied as a lyophilized powder. Preservative free. Reconstitute with 50ul of 5mM sodium phosphate, pH 8.0.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAcidic Fibroblast Growth Factor, Beta Endothelial Cell Growth Factor


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