Fibroblast Growth Factor 4, Recombinant, Human (FGF-4, Heparin Secretory Transforming Protein 1, HSTF-1, HST-1, HST, Transforming Protein KS3, Heparin-binding Growth Factor 4, HBGF-4, HSTF1, KS3)
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| FGF4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF4 signals through the FGFR1c, 2c, 3c, and 4. Recombinant human FGF4 is a 19.7kD protein consisting of 182 amino acids. | | | Catalog # | F4210-50 | | Biological Activity | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is 0.5ng/ml, corresponding to a speci c activity of | | 2x10e6 units/mg. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS, 0.1% HSA or BSA, aliquot and store at -20°C. Reconstituted product is stable for 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Country of Origin | USA | | Molecular Weight | 19.7kD | | Source | Recombinant, human (E. coli) | | Purity | 95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug). | | Form | Supplied as a lyophilized powder from 10mM sodium phopshate, pH 7.4, 100mM sodium chloride. | | Reconstitution | Reconstitute in sterile ddH2O to 0.1-1mg/ml. This solution can be diluted into other aqueous buffers. | | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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