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You are here:Home » Growth Factors, Cytokines » Growth Factors-FGF » Fibroblast Growth Factor 4, Recombinant, Human (FGF-4, Heparin Secretory Transforming Protein 1, HSTF-1, HST-1, HST, Transforming Protein KS3, Heparin-binding Growth Factor 4, HBGF-4, HSTF1, KS3)

Fibroblast Growth Factor 4, Recombinant, Human (FGF-4, Heparin Secretory Transforming
Protein 1, HSTF-1, HST-1, HST, Transforming Protein KS3, Heparin-binding Growth Factor 4,
HBGF-4, HSTF1, KS3)

Pricing

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Specifications

Fibroblast growth factor 4 is a member of the FGF family, a group of 7 homologous polypeptides that act upon a variety of cells and produce biological actions that may include cell proliferation, migration and differentiation. FGF4, also known as oncogene products hst1 and KFGF, has strong transforming potential and is a potent angiogenic factor, being expressed in several highly vascularized tumors.
Catalog #F4210-50A
SourceRecombinant corresponding to 182aa from human Fibroblast Growth Factor 4 expressed in E. coli.
Molecular Weight~19.7kD
Endotoxin 0.1ng/ug
Biological ActivityED50 0.5ng/ml ( 2x10e6 units/mg), determined by the dose dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors. FGF-4 is a heparin binding growth factor expressed by tumor cells and embryonic cells which has mitogenic activity with fibroblasts and endothelial cells.
ApplicationsSuitable for use in Neutralization. Other applications not tested.
Recommeded DilutionsOptimal dilution to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C with a carrier protein. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight19.7kD
SourceE. coli
Purity~95% (SDS-PAGE). Purified by sequential chromatography.
ConcentrationNot determined
FormSupplied as a lyophilized powder from 10mM sodium phosphate, pH 7.4, 100mM sodium chloride, 1.25mg BSA. Reconstitute with sterile ddH2O to 0.1-1mg/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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