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You are here:Home » Molecular Biology » MB-Growth Factors-FGF » Fibroblast Growth Factor 18, Recombinant, Human (FGF18)

Fibroblast Growth Factor 18, Recombinant, Human (FGF18)


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The FGFs play key roles in controlling tissue growth, morphogenesis and repair in animals. FGF-18 is a newly discovered heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. Recombinant Human FGF-18 is a 21.2kD protein containing 182aa.
Catalog #F4212-90
Biological ActivityThe ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is 0.5ng/ml, corresponding to a speci c activity of
2x10e6 units/mg.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 5mM Tris and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.e made in assay buffer.
Country of Origin USA
Molecular Weight21.2kD
SourceHuman, recombinant protein expressed in E. coli
Purity95% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug).
FormSupplied as a lyophilized powder from 10mM Tris, pH 8.0.
Reconstitute in 5mM Tris, pH 8.0 to a concentration of 0.1-1mg/ml. Further dilutions should be made in aqueous buffers supplemented with carrier protein, such as 0.1-1% BSA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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