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You are here:Home » Molecular Biology » Growth Factors-FGF » Fibroblast Growth Factor 22, Recombinant, Human (FGF22)

Fibroblast Growth Factor 22, Recombinant, Human (FGF22)

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Specifications

Fibroblast growth factor 22, a protein which in humans is encoded by the FGF22 gene, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth,morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.
Catalog #F4212-94B
Recombinant Human FGF-22 produced in E. coli is a single, non-glycosylated polypeptide chain containing 148 amino acids and having a molecular mass of 17173D.
Biological Activity Measured in a cell proliferation assay using IEC6 cell line (20ng/ml can stimulate the cell proliferation of IEC6 cell line.
AA SequenceThe sequence of the first five N-terminal amino acids was determined and was found to be
Thr-Pro-Ser-Ala-Ser.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight17.2kD
SourceRecombinant, human, E. coli
Purity95% as determined by RP-HPLC; Reducing and non-reducing SDS-PAGE.
FormSupplied as a lyophilized powder. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml, which can be further diluted into other aqueous solutions.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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