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You are here:Home » Antibodies » Abs to Fibronectin » Anti -Fibronectin, Plasma (pFn, FN, FN1, Cold-insoluble Globulin, CIG, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED-B, FINC, FNZ, GFND, GFND2, LETS, MSF)

Anti -Fibronectin, Plasma (pFn, FN, FN1, Cold-insoluble Globulin, CIG, DKFZp686F10164,
DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED-B, FINC, FNZ, GFND, GFND2, LETS, MSF)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B IH
Fibronectins are diverse high molecular weight cell adhesion glycoproteins found in basement membranes, in the interstitial connective tissue matrix, and in soluble in plasma and other body fluids. In adult tissues most fibronectin is produced by hepatocytes (pFn) that differ from locally produced cellular fibronectins. A monoclonal antibody (BF12)has been produced to fibronectin that reacts with both the cellular and plasma forms of the protein and recognizes the cell-binding region in fibronectin. The monoclonal antibody DH1 recognizes only cellular form of Fibronectin. DH1 is specific to the extra domain A (EDA) of the molecule. cFns are found in some basement membranes during development and only in distinct tissues in adult, for instance in smooth muscle and alveolar walls of airways. cFns are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas.
Catalog #F4215-20P
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoBF12
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 1% BSA, 0.1 % sodium azide.
PuritySerum
ImmunogenPurified fibronectin from A8387 fibrosarcoma cells
SpecificityRecognizes the cellular and plasma forms of human fibronectin and recognizes the cell binding region. Species Crossreactivity: Guinea pig
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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