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You are here:Home » Antibodies » Abs to Receptors » Anti -Fibroblast Growth Factor Receptor 1 (FGFR1, Basic Fibroblast Growth Factor Receptor 1, BFGFR, bFGF-R, CD331, CEK, c-fgr, FGFBR, FGFR-1, FLG, FLJ99988, FLT2, Fms-like Tyrosine Kinase 2, H2, H3, H4, H5, HBGFR, KAL2, N-SAM, OGD)

Anti -Fibroblast Growth Factor Receptor 1 (FGFR1, Basic Fibroblast Growth Factor Receptor
1, BFGFR, bFGF-R, CD331, CEK, c-fgr, FGFBR, FGFR-1, FLG, FLJ99988, FLT2, Fms-like Tyrosine
Kinase 2, H2, H3, H4, H5, HBGFR, KAL2, N-SAM, OGD)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH FC
FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig-like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is a widely expressed membrane receptor, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N-cadherin and NCAM.
Catalog #F4305-02G
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1ug/ml
Flow Cytometry: 1:10-1:1000
Immunohistochemistry: 1:10-1:2000
Immunoprecipitation: 1:10-1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8k231
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4. No preservative added.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to human ectodomain of FGFR1b, expressed in E. coli, beginning with proline 23; antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences. Cellular Localization: Cell membrane.
SpecificityRecognizes alpha and beta isoforms of human Fibroblast Growth Factor Receptor 1. Epitope
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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