You are here:Home
»
Antibodies
»
Abs to Membrane Proteins
»
Anti -Fibulin 1 (Basement Membrane Protein 90, BM90)
Anti -Fibulin 1 (Basement Membrane Protein 90, BM90)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
B IP IH FC |
|
| The fibulins are a family of secreted glycoproteins that are components of elastic matrix fibers and basement membranes. Fibulin-1 is an extracellular matrix protein, which can adhere to endothelial cells and regulate their motility and proliferation. Fibulin-1 is overexpressed in estrogen receptor (ER)-positive ovarian carcinomas and several studies suggest a possible role for fibulin-1 as a tumor suppressor. Xie et al. described that fibulin-1 inhibits tumor growth in HT1080 cell lines by suppressing tumor angiogenesis and inducing apoptosis. | | | Catalog # | F4350-25 | | Applications | Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: frozen and paraffin sections | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | 6D395 | | Host | Mouse | | Source | Human | | Concentration | ~0.3mg/ml | | Form | Supplied as a liquid in 20mM Tris, pH 7.4, 1.25M sodium chloride, 0.02% sodium azide. | | Purity | Purified | | Immunogen | Recombinant human fibulin-1. | | Specificity | Recognizes human fibulin-1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
