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You are here:Home » Antibodies » Antibodies-Membrane Proteins » Anti -Fibulin 1 (Basement Membrane Protein 90, BM90)

Anti -Fibulin 1 (Basement Membrane Protein 90, BM90)


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Clone Host Grade Applications
Monoclonal Mouse Purified B IP IH FC
The fibulins are a family of secreted glycoproteins that are components of elastic matrix fibers and basement membranes. Fibulin-1 is an extracellular matrix protein, which can adhere to endothelial cells and regulate their motility and proliferation. Fibulin-1 is overexpressed in estrogen receptor (ER)-positive ovarian carcinomas and several studies suggest a possible role for fibulin-1 as a tumor suppressor. Xie et al. described that fibulin-1 inhibits tumor growth in HT1080 cell lines by suppressing tumor angiogenesis and inducing apoptosis.
Catalog #F4350-25
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: frozen and paraffin sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No6D395
FormSupplied as a liquid in 20mM Tris, pH 7.4, 1.25M sodium chloride, 0.02% sodium azide.
ImmunogenRecombinant protein corresponding to human fibulin-1.
SpecificityRecognizes human fibulin-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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