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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Fibulin 1 (Basement Membrane Protein 90, BM90)

Anti -Fibulin 1 (Basement Membrane Protein 90, BM90)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IP IH FC
The fibulins are a family of secreted glycoproteins that are components of elastic matrix fibers and basement membranes. Fibulin-1 is an extracellular matrix protein, which can adhere to endothelial cells and regulate their motility and proliferation. Fibulin-1 is overexpressed in estrogen receptor (ER)-positive ovarian carcinomas and several studies suggest a possible role for fibulin-1 as a tumor suppressor. Xie et al. described that fibulin-1 inhibits tumor growth in HT1080 cell lines by suppressing tumor angiogenesis and inducing apoptosis.
Catalog #F4350-25
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: frozen and paraffin sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM
Clone No6D395
HostMouse
SourceHuman
Concentration~0.3mg/ml
FormSupplied as a liquid in 20mM Tris, pH 7.4, 1.25M sodium chloride, 0.02% sodium azide.
PurityPurified
ImmunogenRecombinant protein corresponding to human fibulin-1.
SpecificityRecognizes human fibulin-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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