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You are here:Home » Antibodies » Abs to Drugs » Anti -FK-506 (Fujimycin, Tacrolimus)

Anti -FK-506 (Fujimycin, Tacrolimus)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E
FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.
Catalog #F4522-02
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM
Clone No10C251
HostMouse
Concentration~1mg/ml
FormSupplied as liquid TBS, 0.09% sodium azide.
PurityPurified
ImmunogenFK-506-BSA conjugate.
SpecificityRecognizes FK-506.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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