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You are here:Home » Antibodies » Abs to Actin Related Proteins » Anti -FLII (Protein Flightless-1 Homolog, FLIL)

Anti -FLII (Protein Flightless-1 Homolog, FLIL)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Flightless-1 homolog is a 1269aa containing protein with a gelsolin-like actin binding domain and an N-terminal leucine rich protein-protein interaction domain acts as a coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and in conjunction with NCOA2 and CARM1. FLIIH is involved in estrogen hormone signaling and early embryonic development. The protein also plays a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration. Deletion of the FLII gene may be a cause of Smith-Magenis syndrome (SMS).
Catalog #F4544-30
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlBrain
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa90-140 of human FLIIH.
SpecificityRecognizes human FLII. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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