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You are here:Home » Antibodies » Abs to Receptors, Tyrosine Kinase » Anti -Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2)

Anti -Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Flk-1/KDR /VEGFR2, a cell membrane receptor kinase, is a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis. It contains seven immunoglobulin-like sequences in the extracellular domain and exhibits sequence similarity to Flt-1 and Flt-4.
Catalog #F4565-09
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended dilutionsImmunohistochemistry (Formalin/paraffin): 1:25. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min. Optimal dilutions to be determined by the researcher.
Positive Control Angiosarcoma
Cellular Localization Cytoplasmic
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.6, 0.2% BSA and 15mM sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide derived from the C-terminal of human Flk-1
SpecificityRecognizes Flk-1. Species Crossreactivity: Human, Mouse and Rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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