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You are here:Home » Antibodies » Antibodies-Tyrosine Kinases » Anti -FLT3, NT (Tyrosine-protein Kinase Receptor FLT3, Fms-like Tyrosine Kinase 3, FLT-3, STK1, FL Cytokine Receptor, Stem Cell Tyrosine Kinase 1, STK-1, CD135)

Anti -FLT3, NT (Tyrosine-protein Kinase Receptor FLT3, Fms-like Tyrosine Kinase 3, FLT-3,
STK1, FL Cytokine Receptor, Stem Cell Tyrosine Kinase 1, STK-1, CD135)


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Clone Host Grade Applications
Polyclonal Rabbit Purified E B FC
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Catalog #F4600-07A
ApplicationsSuitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
ConcentrationAs Reported
FormSupplied as a liquid in PBS, 0.09% sodium azide
PurityPurified by ammonium sulfate precipitation
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 33-64 in the N-terminal region of human FLT3, UniProt Accession #P36888.
SpecificityRecognizes human FLT3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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