Anti -Flt3 Ligand (Fms-like Tyrosine Kinase 3 Ligand, flk2 Ligand, Fms Related Tyrosine
Kinase 3 Ligand, Flt3-L, Flt 3L, Flt3 L, FLT3 LG, Flt3L, FLT3LG, SL Cytokine)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B IH IC FC |
|
| Human Flt3 ligand (Flt3L) stimulates early hematopoiesis by activating a type III tyrosine kinase receptor on primitive bone marrow stem cells. The crystal structure of soluble Flt3L reveals that it is a homodimer of two short chain alpha-helical bundles (1). Flt3 is a hematopoietic growth factor that stimulates cells via specific and structurally related tyrosine kinase receptors on the cell surface (2). This growth factor stimulated the proliferation of hematopoietic progenitor cells isolated from mouse fetal liver or adult mouse bone marrow (3). | | | Catalog # | F4600-07F | | Applications | Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry, Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:10,000-1:50,000 (10ng) | | Immunohistochemistry: 1:50-1:100 | | Immunocytochemistry: 1:100-1:250 | | Flow Cytometry: 1:10 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9E317 | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol. | | Purity | Supernatant | | Immunogen | Synthetic peptide corresponding to residues within human Flt3-L. | | Specificity | Recognizes human Human Flt3 ligand. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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