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Specifications

Non-steroidal anti-inflammatory drugs, usually abbreviated to NSAIDs or NAIDs , are drugs with analgesic, antipyretic and, in higher doses, anti-inflammatory effects - they reduce pain, fever and inflammation. Most NSAIDs act as nonselective inhibitors of the enzyme cyclooxygenase, inhibiting both the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes. Cyclooxygenase catalyzes the formation of prostaglandins and thromboxane from arachidonic acid . Prostaglandins are short-lived substances made from fatty acids that play a role in many body functions. They influence pain signals, regulation of inflammation, maintenance of tissues such as the lining of the stomach, blood clotting and stimulation of cells into action. In whole the NSAIDs prevent the prostaglandins from ever being synthesized, therefore reducing or eliminating the pain.
Catalog #	F5033-01D
Applications	Suitable for use in ELISA. Other applications not tested.
Recommended Dilution	ELISA: 1:320
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. HRP conjugates are sensitive to light.
Concentration	Not determined
Form	Supplied as a liquid. Labeled with horseradish peroxidase (HRP).
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.