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You are here:Home » Antibodies » Abs to Cell Markers » Anti -Follicular Dendritic Cells

Anti -Follicular Dendritic Cells

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH
Follicular dendritic cells (FDC) are cells of the immune system found in lymph follicles of secondary lymphoid organs and tertiary lymphoid organs. They are probably not of hematopoietic origin, though they look similar to true dendritic cells due to their filiform dendritic processes, but are of stromal, mesenchymal origin. The term FDC was introduced to distinguish them from other stromal cells localizing in the B cell follicles, the reticular fibroblast cells. FDCs are originally defined as cells within lymphoid follicles, which trap immune complexes. Their classification in MeSH. They assist in B cell maturation by the presentation of intact antigen to the B cells. This occurs in the germinal centers of peripheral lymphoid organs and induces class switching and proliferation.
Catalog #F5923-51
ApplicationsSuitable for use in Immunohistochemistry (frozen and paraffin). Other applications not tested.
Recommended DilutionImmunohistochemistry (frozen): 0.4ug/ml
Immunohistochemistry (paraffin): 2ug/ml
Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10C265
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder from PBS, 0.01% Kathon, 5mg/ml BSA. Reconstitute with 500ul sterile 40-50% glycerol, ddH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenEnriched human blood dendritic cells
SpecificityRecognizes human Follicular Dendritic Cells.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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