Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Actin Related Proteins » Anti -FHOD1 (FH1/FH2 Domain-containing Protein 1, Formin Homolog Overexpressed in Spleen 1, FHOS, Formin Homology 2 Domain-containing Protein 1, FHOS, FHOS1)

Anti -FHOD1 (FH1/FH2 Domain-containing Protein 1, Formin Homolog Overexpressed in Spleen
1, FHOS, Formin Homology 2 Domain-containing Protein 1, FHOS, FHOS1)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E
FHOD1, a predominantly cytoplasmic protein, is a 1164aa containing member of formin:diaphanous family of proteins that contains a FH1 (formin homology 1) domain, a FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding:formin homology 3) domain. FHOD1 self-associates via the FH2 domain and binds to F-actin via its N-terminus and also to the cytoplasmic domain of CD21 via its C-terminus. Function of FHOD1 include the assembly of F-actin structures, such as stress fibers, and depends on the Rho-ROCK cascade for its activity. Reports suggest the role of FHOD1 in the coordination of microtubules with actin fibers and also in cell elongation. Endogenous FHOD1 interacts directly with Rac1 in a guanine nucleotide-independent manner and thus activates transcription from the serum response element. Ubiquitous expression of FHOD1 is seen in most of the tissues with abundance in the spleen and a variety of human cell lines.
Catalog #F6002-67A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.025% sodium azide, 50% glycerol.
PuritySerum.
ImmunogenSynthetic peptide corresponding to aa348-365 of human FHOD1 GGRRERRKPSSEEGKRSR.
SpecificityRecognizes human FHOD1. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links