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You are here:Home » Antibodies » Abs to Actin Related Proteins » Anti -FHOD3 (FH1/FH2 Domain-containing Protein 3, Formactin-2, Formin Homolog Overexpressed in Spleen 2, hFHOS2, FHOS2, KIAA1695)

Anti -FHOD3 (FH1/FH2 Domain-containing Protein 3, Formactin-2, Formin Homolog
Overexpressed in Spleen 2, hFHOS2, FHOS2, KIAA1695)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
FHOD3 is a novel member of the formin homology family playing an important role in regulation of the actin cytoskeleton. It contains aDD (diaphanous auto regulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. FHOD3 is a cytoplasmic protein where the main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. FHOD3 is a 1422aa containing formin-related actin-organizing protein that may cause stress fiber formation together with cell elongation and may associate with nestin/NES-based interfilament (IF). Expression of FHOD3 is seen mainly in heart, kidney and brain.
Catalog #F6002-69A
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (formalin fixed paraffin embedded): 15ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1250-1300 of human FHOD3 (CRA_d).
SpecificityRecognizes human FHOD3. Species Crossreactivity: chicken, canine, equine, bovine, mouse, opossum.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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