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You are here:Home » Molecular Biology » Growth Factors-Fraktaline » Fractalkine, Recombinant, Human (FKN, A-152E5.2, ABCD-3, Chemokine (C-X3-C Motif) Ligand 1, C-X3-C Motif Chemokine 1, C3Xkine, CXC3, CXC3C, CX3CL1, Neurotactin, NTN, NTT, Small Inducible Cytokine D1, SCYD1)

Fractalkine, Recombinant, Human (FKN, A-152E5.2, ABCD-3, Chemokine (C-X3-C Motif) Ligand
1, C-X3-C Motif Chemokine 1, C3Xkine, CXC3, CXC3C, CX3CL1, Neurotactin, NTN, NTT, Small
Inducible Cytokine D1, SCYD1)

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Specifications

AHP453B is specific for human fractalkine, otherwise known as CX3CL1, a 397aa CX3C chemokine which signals through the CX3CR1 receptor and is expressed by various tissues including the brain, testis, lung, heart, kidney, colon and skeletal muscle.
Catalog #F6069-95H
Adhesion of fractalkine to the CX3CR1 receptor triggers the chemotaxis and adhesion of leukocytes, including T cells, monocytes and NK cells and studies have suggested that fractalkine is involved in the regulation of brain microglia during neuroinflammatory processes (1) and may play a role in dendritic cell–mediated host defense against invading pathogens such as Legionella pneumophila (2).
SourceRecombinant corresponding to human Fractalkine.
ApplicationsSuitable for use in Functional Assays. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and Stability
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceHuman
PurityPurified by immunoaffinity chromatography.
FormSupplied as a lyophilized powder in PBS. Preservative free. Reconstitute with sterile PBS to 1mg/ml containing 0.1% BSA.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCX3C Membrane-anchored Chemokine, Small Inducible Cytokine Subfamily D Member 1


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