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You are here:Home » Antibodies » Abs to RNA Binding Proteins » Anti -FMR1 (Fragile X Mental Retardation 1 Protein, FMRP, Protein FMR-1)

Anti -FMR1 (Fragile X Mental Retardation 1 Protein, FMRP, Protein FMR-1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Fragile X Mental Retardation Protein (FMRP) is an RNA-Binding protein that is associated to polysomes and may be involved in the transpot of mRNA from the nucleus to the cytoplasm. Defects in FMR1 are the cause of Fragile X syndrome, which is a common genetic disease characterized by moderate to severe mental retardation, macroorchidism, large ears, prominent jaw, and high-pitched, jocular speech. The defect in most fragile X syndrome patients results from an amplication of a CGG repeat regions with is directly in front of the coding region.
Catalog #F6072-01A
ApplicationsSuitable for use in Peptide ELISA and Western Blot. Other applications not tested.
Recommended DilutionsPeptide ELISA: detection limit is 1:128,000
Western Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS NumberN/A
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic peptide corresponding to C-RTGKDRNQKKEKPD, from the C-terminus of human FMR1 (NP_002015.1).
Species Sequence HomologyCanine, mouse and rat
SpecificityRecognizes human FMR1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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