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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -Frizzled 3 (Frizzled Family Receptor 3, Frizzled-3, FZD3, Fz-3, FZD3, hFz3)

Anti -Frizzled 3 (Frizzled Family Receptor 3, Frizzled-3, FZD3, Fz-3, FZD3, hFz3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Frizzled-3 (FZD3) is a Frizzled Receptor that mediates Wnt signaling. It is widely expressed, mostly in brain and urogenital tissues. FZD3 is also expressed in the epidermis and developing hair follicles. FZD3 has been implicated in the development of axon tracts in the forebrain. A truncated form of FZD3 exists due to alternative splicing. FZD3 expression has been documented in blood, brain, colon, kidney, lung, lymph node, ovary, pancreas, skeletal muscle, skin, spinal cord, stomach, urogenital tract, and uterus. ESTs have been isolated from amnion, brain, colon, eye, heart, kidney, lymph, skin, and testis libraries.
Catalog #F6401-11G
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 5ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Brain, Neurons and glia
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the N-terminal extracellular domain of human FZD3.
SpecificityRecognizes human FZD3. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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