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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -FZD3 (Frizzled 3, Frizzled-3, Fz-3, hFz3)

Anti -FZD3 (Frizzled 3, Frizzled-3, Fz-3, hFz3)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
Frizzled-3 (FZD3) is a Frizzled Receptor that mediates Wnt signaling. It is widely expressed, mostly in brain and urogenital tissues. FZD3 is also expressed in the epidermis and developing hair follicles. FZD3 has been implicated in the development of axon tracts in the forebrain. A truncated form of FZD3 exists due to alternative splicing. FZD3 expression has been documented in blood, brain, colon, kidney, lung, lymph node, ovary, pancreas, skeletal muscle, skin, spinal cord, stomach, urogenital tract, and uterus. ESTs have been isolated from amnion, brain, colon, eye, heart, kidney, lymph, skin, and testis libraries.
Catalog #F6401-12A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-DDQRSKAGSIHSK, from FZD3, at the internal region of the protein (NP_059108.1).
SpecificityRecognizes FZD3. Species sequence homology: Human, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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