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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -Frizzled 5 (Frizzled Family Receptor 5, Frizzled-5, Fz-5, FZD5, FzE5, hFz5, C2orf31, DKFZp434E2135, MGC129692)

Anti -Frizzled 5 (Frizzled Family Receptor 5, Frizzled-5, Fz-5, FZD5, FzE5, hFz5, C2orf31,
DKFZp434E2135, MGC129692)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway. FZD5 has been reported to be expressed in fetal kidney, fetal and adult liver, fetal lung, and adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, and prostate libraries. FZD5 was cloned from a retina cDNA library.
Catalog #F6401-18C
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 24ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Synovium, Rheumatoid Arthritis
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the 3rd cytoplasmic domain of human FZD5.
SpecificityRecognizes human FZD5.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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