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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -Frizzled 7, CT (Frizzled-7, Frizzled (Drosophila) Homolog of 7, Frizzled Homolog 7, Fz 7, Fz-7, FZD7, FzE3, hFz7, Homolog of Drosophila Frizzled 7)

Anti -Frizzled 7, CT (Frizzled-7, Frizzled (Drosophila) Homolog of 7, Frizzled Homolog 7,
Fz 7, Fz-7, FZD7, FzE3, hFz7, Homolog of Drosophila Frizzled 7)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
FZD7 is a receptor for Wnt signaling proteins. FZD7 down regulates the functions of the tumor suppressor gene APC and thereby enhances beta catenin-mediated signals. FZD7 is highly expressed adult skeletal muscle and foetal kidney. High expression is observed in the foetal lung, placenta, adult heart and brain tissues. It is specifically expressed in squamous cell oesophageal carcinomas.
Catalog #F6401-32F
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:64,000
Western Blot: 0.3-1ug/ml
Immunohistochemistry (Formalin-fixed, paraffin-embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-RFYHRLSHSSKGET from human FZD7 at C-terminal.
SpecificityRecognizes human FZD7. Species sequence homology: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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