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Anti -FOXP3 (Forkhead Box P3, AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID)
Anti -FOXP3 (Forkhead Box P3, AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Purified |
E B IH IC |
|
| FoxP3 is a 48kD forkhead transcription factor family member, which was originally identified as the novel protein scurfin. FoxP3 functions as a DNA binding protein that represses transcription, and is reported to be involved in the regulation of T cell activation, differentiation and homeostasis. FoxP3 is predominantly expressed within the nuclei of CD25 +CD4 + regulatory T cells (Tr). This population of FoxP3+CD25+CD4+ Tr cells plays an essential role in controlling autoimmunity. | | | Catalog # | F9050-12 | | Applications | Suitable for use in ELISA, Immunocytochemistry, Immunohistochemistry and Western Blot. Other applications have not been tested. | | Recommended Dilutions | ELISA (direct and indirect): 1:2000-1:10,000 | | Western Blot: 1:2000-1:5000 using ECL. Suggested blocking and dilution buffer is TBST, 0.05% Tween-20 and 5% skim milk. Suggested incubation time is 1 hour at RT. | | Immunohistochemistry: Frozen | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 6D401 | | Host | Rat | | Source | Mouse | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4. No preservative added. | | Purity | Purified | | Immunogen | Recombinant mouse FOXP3 (forkhead box protein P3) | | Specificity | Recognizes both natural and recombinant mouse FOXP3. Detects a band of ~46-49kD by Western Blot. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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