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Anti -FUS (Fusion, FUS1, TLS, Pigpen, POMp75, Fusion (Involved in t(12,16) in Malignant Liposarcoma), Translocated in Liposarcoma Protein)
Anti -FUS (Fusion, FUS1, TLS, Pigpen, POMp75, Fusion (Involved in t(12,16) in Malignant
Liposarcoma), Translocated in Liposarcoma Protein)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| FUS is a nucleic acid-binding protein whose N-terminal half functions as a transcriptional activator domain in fusion oncoproteins found in human leukemias and liposarcomas. FUS has been reported to be associated with the nuclear matrix and has been implicated in transcription, pre-mRNA splicing processes, spliceosome assembly, and promoting undifferentiated endothelial cells. | | | Catalog # | F9205-03 | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | As reported | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | A synthetic peptide which maps to a region between residues 500 and the C-terminus (residue 526) of human fusion (involved in t(12;16) in malignant liposarcoma) using the numbering given in SwissProt entry P35637 (GeneID 2521). | | Specificity | Specific for human FUS protein. Other species not tested. Reactivity with mouse (but not X. laevis) FUS is likely owing to identity of sequence between mouse and human FUS at the site to which the epitope maps. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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