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You are here:Home » Antibodies » Abs to Disease Markers » Anti -FUS (Fusion, FUS1, TLS, Pigpen, POMp75, Fusion (Involved in t(12,16) in Malignant Liposarcoma), Translocated in Liposarcoma Protein)

Anti -FUS (Fusion, FUS1, TLS, Pigpen, POMp75, Fusion (Involved in t(12,16) in Malignant
Liposarcoma), Translocated in Liposarcoma Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
FUS is a nucleic acid-binding protein whose N-terminal half functions as a transcriptional activator domain in fusion oncoproteins found in human leukemias and liposarcomas. FUS has been reported to be associated with the nuclear matrix and has been implicated in transcription, pre-mRNA splicing processes, spliceosome assembly, and promoting undifferentiated endothelial cells.
Catalog #F9205-04
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionsWestern Blot: 1:10,000-50,000
Immunoprecipitation: 2-5ug/mg
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in Tris-citrate/phosphate buffer, pH 7.5, 0.09% sodium azide
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide corresponding to aa1-50 of human fusion (involved in t(12;16) in malignant liposarcoma) using the numbering given in SwissProt entry P35637 (GeneID 2521).
SpecificityRecognizes human FUS protein, Mr 53kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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