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You are here:Home » Antibodies » Abs to Splicing Factors » Anti -FUSIP1 (FUS-interacting Protein (Serine-arginine Rich) 1, FUS Interacting Serine Arginine Rich Protein 1, 40kD SR-repressor Protein, FUSIP2, NSSR, OTTHUMP00000015774, Serine Arginine Repressor Protein 40kD, SFRS13, Splicing Factor SRp38, SRp38, SRp40, TLS

Anti -FUSIP1 (FUS-interacting Protein (Serine-arginine Rich) 1, FUS Interacting Serine
Arginine Rich Protein 1, 40kD SR-repressor Protein, FUSIP2, NSSR, OTTHUMP00000015774,
Serine Arginine Repressor Protein 40kD, SFRS13, Splicing Factor SRp38, SRp38, SRp40, TLS

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. FUSIP1 can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. This antibody is specific for isoform 3 of FUSIP1.
Catalog #F9215-50
ApplicationsSuitable for use Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5 mg/ml,
Optimal dilutions to be determined by the researcher.
Positve ControlHepG2 whole cell extracts. ~22kDa
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in Tris-citrate/phosphate, pH 7-8, 0.01% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to an internal portion of the human protein (within residues 100-200). [O75494]
SpecificityRecognizes human FUSIP1. Species sequence homology: 100% to mouse FUSIP1 isoform 3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesFUS-interacting Serine-arginine-rich Protein 1


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