Anti -Galectin-3 (Gal-3, 35kD Lectin, Carbohydrate-binding Protein 35, CBP 35,
Galactose-specific Lectin 3, Galactoside-binding Protein, GALBP, IgE-binding Protein,
L-31, Laminin-binding Protein, Lectin L-29, Mac-2 Antigen, LGALS3, MAC2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B FC IF |
|
| Galectin-3 (galactose-specific lectin 3) is a 30-32kD glycoprotein, also known as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and eBP. It is a member of the animal B-galactoside-binding lectin family that is expressed in the cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to B-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Structurally, Galectin-3 possesses NWGR motif that is conserved in the BH-1 domain of the BCL-2 family and functions as an apoptotic molecule. | | | Catalog # | G1044-50J | | Applications | Suitable for use in Immunofluorescence, Flow Cytometry and Western Blot. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 0.5ug/10e5 cells in 100ul | | Western Blot: 0.5-1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1, k | | Clone No | Gal397 | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Partial recombinant corresponding to aa151-251 of human Galectin-3. | | Specificity | Recognizes human Galectin-3. Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Galectin-3 (Gal-3, 35kD Lectin, Carbohydrate-binding Protein 35, CBP 35, Galactose-specific Lectin 3, Galactoside-binding Protein, GALBP, IgE-binding Protein, L-31, Laminin-binding Protein, Lectin L-29, Mac-2 Antigen, LGALS3, MAC2) |
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