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Specifications

Galiellalactone was originally isolated from Galiella rufa as a plant growth regulator. Recently it was shown to inhibit IL-6 induced SEAP expression with IC50 values of 250-500nM by blocking the binding of the activated Stat3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation of the Stat3 transcription factor.
Catalog #	G1044-62
Solubility	Soluble in ethanol, methanol, DMF or DMSO.
Storage and Stability	Lyophilized powder may be stored at -20°C for short-term only. Reconstitute with ethanol, methanol, DMF or DMSO, and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	133613-71-5
Molecular Formula	C11H14O3
Molecular Weight	194.2
Source	Unidentified fungus, MST-FP1889
Purity	90% by HPLC
Form	Supplied as a white to light tan powder
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.