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You are here:Home » Biochemicals » Biochem-Antibiotics » Galiellalactone



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Galiellalactone was originally isolated from Galiella rufa as a plant growth regulator. Recently it was shown to inhibit IL-6 induced SEAP expression with IC50 values of 250-500nM by blocking the binding of the activated Stat3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation of the Stat3 transcription factor.
Catalog #G1044-62
SolubilitySoluble in ethanol, methanol, DMF or DMSO.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number133613-71-5
Molecular FormulaC11H14O3
Molecular Weight194.2
SourceUnidentified fungus, MST-FP1889
Purity90% by HPLC
FormSupplied as a white to light tan powder
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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