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Anti -Gastric Inhibitory Polypeptide (GIP)
Anti -Gastric Inhibitory Polypeptide (GIP)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH |
|
| Human gastric inhibitory polypeptide (GIP) is a 42aa peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from ~50% identity for glucagon to 30% identity for GLP-2). | | | Catalog # | G2019F | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:2000; Using glutaraldehyde-linked GIP-OA (molar ratio 4:1) coated at 1ug/ml (or GIP coated directly at 2ug/ml). G2019F binds free GIP in solution. | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Sp2/mIL-6 myeloma cells with spleen cells from NMRI x Balb/c mice. | | Culture Medium | RPMI 1640 with 10% fetal calf serum | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 6F106 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Also available without azide. See G2019F1. | | Purity | Purified by Protein A/G affinity chromatography. | | Immunogen | Synthetic human gastric inhibitory polypeptide | | Specificity | Recognizes human Gastric Inhibitory Polypeptide (GIP). Binds free GIP in solution. Crossreacts up to 10% with PACAP and human GLP-2. < 0.1% crossreactivity with glucagon, GLP-1 and VIP. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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