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G2022-98 Rabbit Anti-GC (Glucosylceramidase, GLUC, Acid beta-Glucosidase, GBA, Alglucerase, beta-Glucocerebrosidase, D-glucosyl-N-acylsphingosine Glucohydrolase, Imiglucerase)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P04062
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu Mo
Accession #
NP_000148.2
Shipping Temp
Blue Ice
Storage Temp
-20°C
EC=3.2.1.45, Late Cornified Envelope Protein 6A, LCE6A, C1orf44

GC is a protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism.

Applications
Suitable for use in ELISA, Immunohistochemistry, Indirect Flow Cytometry and Western Blot. Other applications not tested.
Recommended Dilutions
Immunohistochemistry (FFPE): 1:500 Western Blot: 1:1000 Indirect Flow Cytometry: 1:25 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 337-365 of human GC. Species Sequence Homology: bovine and porcine
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human GC. Species Crossreactivity: mouse
References
1. Jamrozik,Z., et.al., J. Neurol. 257(3), 459-460 (2010). 2. Mao,X.Y., et.al., Neurosci. Lett. 469(2), 256-259 (2010).
USBio References
No references available
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