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Abs to Neurotrophins
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Anti -GFR alpha 2 (GDNF family receptor alpha-2, GFR-alpha-2, Neurturin receptor alpha, NTNR-alpha, NRTNR-alpha, TGF-beta-related neurotrophic factor receptor 2, GDNF receptor beta, GDNFR-beta, RET ligand 2)
Anti -GFR alpha 2 (GDNF family receptor alpha-2, GFR-alpha-2, Neurturin receptor alpha,
NTNR-alpha, NRTNR-alpha, TGF-beta-related neurotrophic factor receptor 2, GDNF receptor
beta, GDNFR-beta, RET ligand 2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
B IH |
|
| Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. | | | Catalog # | G2033-31 | | Cellular Localization | Cell membrane; lipid-anchor; GPI-anchor (By similarity). | | Alternative Products | 2 named isoforms produced by alternative splicing. | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material. | | Purity | Serum | | Immunogen | A synthetic peptide (PRVEKTPSLPDDLSD) as a part of human GFR alpha-2 protein (aa: 376-390) conjugated to KLH. | | Specificity | Western blot analysis indicates a high level of specificity to GFR alpha-2 for this antiserum. Species Crossreactivity: This antibody is known to react with rat GFR alpha-2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | GDNF family receptor alpha-2, GFR-alpha-2, Neurturin receptor alpha, NTNR-alpha, NRTNR-alpha, TGF-beta-related neurotrophic factor receptor 2, GDNF receptor beta, GDNFR-beta, RET ligand 2 |
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