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Gilvocarcin M (Anandimycin B, Toromycin B, Antibiotic 1072A)
Gilvocarcin M (Anandimycin B, Toromycin B, Antibiotic 1072A)
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| Gilvocarcin M is the minor analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin M contains a methyl group in the 8-position and is less active than the vinyl analogue (gilvocarcin V), which is thought to act as an inhibitor of human topoisomerase II. Gilvocarcin M displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research on the gilvocarcins suggests that they act as photoactivated crosslinkers of DNA to histones. | | | Catalog # | G2034-45 | | Purity | > 95% by HPLC | | Solubility | Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. | | Related to | Chrysomycin A, Chrysomycin B, Gilvocarcin V, O-Deacetyl-ravidomycin | | CAS Number | 77879-89-1 | | Molecular Formula | C26H26O9 | | Molecular Weight | 482.5 | | Source | Streptomyces sp. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Anandimycin B, Toromycin B, Antibiotic 1072A |
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