Anti -GIPC3 (PDZ Domain-containing Protein GIPC3, C19orf64)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B Gel |
|
| GIPC proteins are multifunctional proteins which play a significant role in vesicular trafficking, signal transduction, cytoskeletal organization, embryogenesis and carcinogenesis. These are involved in multi-protein interactions which include C-terminus of GAIP/RGS19, FZD class of WNT receptor, IGF-1 receptor, TrkA, TGF-beta type III receptor, integrin alpha6A subunit, and a transmembrane glycoprotein 5T4. GIPC3, a 36kD protein, is a novel member of this family. It is a human ortholog to Xenopus Kermit and Drosophila LPO9416 and consists of a central PDZ domain, GH1 and GH2 domains and a C-terminal ACP domain. Northern Blot analysis and RNA dot blot analysis have detected a ubiquitous expression of GIPC3 in adult and fetal tissues, with an increased expression observed in small intestine, jejunum, parietal lobe of brain, lymph node, fetal liver and fetal thymus. | | | Catalog # | G2034-56A | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 0.2-1.5ug/ml | | ELISA: >1:32,000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human heart | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to EGAAAREARGTET, from the N-terminus of the protein sequence according to NP_573568. | | Specificity | Recognizes human GIPC3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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