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You are here:Home » Antibodies » Abs to G Proteins » Anti -GIPC3 (PDZ Domain-containing Protein GIPC3, C19orf64)

Anti -GIPC3 (PDZ Domain-containing Protein GIPC3, C19orf64)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
GIPC proteins are multifunctional proteins which play a significant role in vesicular trafficking, signal transduction, cytoskeletal organization, embryogenesis and carcinogenesis. These are involved in multi-protein interactions which include C-terminus of GAIP/RGS19, FZD class of WNT receptor, IGF-1 receptor, TrkA, TGF-beta type III receptor, integrin alpha6A subunit, and a transmembrane glycoprotein 5T4. GIPC3, a 36kD protein, is a novel member of this family. It is a human ortholog to Xenopus Kermit and Drosophila LPO9416 and consists of a central PDZ domain, GH1 and GH2 domains and a C-terminal ACP domain. Northern Blot analysis and RNA dot blot analysis have detected a ubiquitous expression of GIPC3 in adult and fetal tissues, with an increased expression observed in small intestine, jejunum, parietal lobe of brain, lymph node, fetal liver and fetal thymus.
Catalog #G2034-56A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.2-1.5ug/ml
ELISA: >1:32,000
Optimal dilutions to be determined by the researcher.
Positive ControlHuman heart
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to EGAAAREARGTET, from the N-terminus of the protein sequence according to NP_573568.
SpecificityRecognizes human GIPC3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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