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You are here:Home » Antibodies » Abs to Ion Channel » Anti -GIRK2 (G-Protein-activated Inward Rectifier Potassium Channel 2, GIRK-2, BIR1, Inward Rectifier K(+) Channel Kir3.2, KATP-2, Potassium Channel, Inwardly Rectifying Subfamily J Member 6, KCNJ6, KATP2, KCNJ7)

Anti -GIRK2 (G-Protein-activated Inward Rectifier Potassium Channel 2, GIRK-2, BIR1,
Inward Rectifier K(+) Channel Kir3.2, KATP-2, Potassium Channel, Inwardly Rectifying
Subfamily J Member 6, KCNJ6, KATP2, KCNJ7)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
GIRK2 is a potassium channel that may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Catalog #G2035-05B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Brain (Substantia Nigra) lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH7.3, 0.5% BSA, 0.02% sodium azide
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-SSKLNQHAELET, from the C-terminus of human GIRK2. (NP_002231.1)
SpecificityRecognizes human GIRK2. Species Sequence Homology: canine, mouse and rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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