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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -Gli2 (GLI-Kruppel Family Member GLI2, THP2, Oncogene GLI2, Tax Helper Protein 2, Tax Responsive Element 2 Holding Protein, Tax-responsive Element 25 bp Sequence Binding Protein, Zinc Finger Protein GLI2)
Anti -Gli2 (GLI-Kruppel Family Member GLI2, THP2, Oncogene GLI2, Tax Helper Protein 2, Tax
Responsive Element 2 Holding Protein, Tax-responsive Element 25 bp Sequence Binding
Protein, Zinc Finger Protein GLI2)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E |
|
| This protein belongs to the C2H2 type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes Greig cephalopolysyndactyly syndrome, Pallister Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. | | | Catalog # | G2035-53C | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:2000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to DLKEDLDRDDCKQE, from the internal region of the protein sequence according to NP_005261.2. | | Specificity | Recognizes GLI2. Species sequence homology: human and mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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