Anti -GLI-3 (GLI-Kruppel Family Member GLI3 (Greig Cephalopolysyndactyly Syndrome), GLI
Family Zinc Finger 3, GLI3, ACLS, GCPS, PAPA, PAP-A, PAPA1, PAPB, PHS, PPDIV, Zinc Finger
Protein GLI3)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E |
|
| Gli-3 (also known as Zinc Finger Protein Gli-3 or GLI-Kruppel family member GLI-3) belongs to the GLI C2H2-type zinc-finger protein family and contains 5 C2H2-type zinc fingers. Gli-3 is very important for normal limb and brain development and is implicated in the transduction of Shh signal. Gli-3 is a nuclear protein expressed in a wide variety of normal adult tissues, including lung, colon, spleen, placenta, testis, and myometrium. Defects in Gli-3 are the cause of Greig cephalo-polysyndactyly syndrome (GCPS); an autosomal dominant disorder-affecting limb and craniofacial development. Two isoforms of human Gli-3 have been reported. One is the fulllength protein at ~170-190kD and the other is a truncated isoform at ~80kD. | | | Catalog # | G2035-54F | | Applications | Suitable for use in ELISA. Other applications not tested. | | Recommended Dilution | ELISA: 1:16,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-HNKRSKIKPDED, from the internal region of the protein sequence according to NP_000159.2. | | Specificity | Recognizes GLI3. Species sequence homology: human, mouse, rat, canine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -GLI-3 (GLI-Kruppel Family Member GLI3 (Greig Cephalopolysyndactyly Syndrome), GLI Family Zinc Finger 3, GLI3, ACLS, GCPS, PAPA, PAP-A, PAPA1, PAPB, PHS, PPDIV, Zinc Finger Protein GLI3) |
External Links
|
