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You are here:Home » Antibodies » Abs to Heat Shock Proteins » Anti -Glucose Regulated Protein 94 (Grp94, gp96, ECGP, Endoplasmin, Heat Shock Protein 90kD beta Member 1, HSP90b1, Stress Inducible Tumor Rejection Antigen gp96, Tumor Rejection Antigen 1, TRA1)

Anti -Glucose Regulated Protein 94 (Grp94, gp96, ECGP, Endoplasmin, Heat Shock Protein
90kD beta Member 1, HSP90b1, Stress Inducible Tumor Rejection Antigen gp96, Tumor
Rejection Antigen 1, TRA1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Glucose-regulated proteins are a class of proteins which are synthesized in response to glycose deprivation. These proteins, along with the closely related heat shock proteins may be grouped together as a family of stress-response proteins (srp). Elevated levels of srp have been observed in some cancer cells and may be an indication of the biological stresses that influence tumor growth. In a study of 398 breast cancer patients, high levels of each of the srps predicted a shorter desease-free survival in node-negative patients. High levels of srp were also correlated with high levels of cathepsin D, suggesting srp may also increase the metastatic and invasive potential.
Catalog #G3057-40L
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.01-0.03ug/ml
Optimal dilutions to be determined by the researcher.
Positive Control3T3 lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KEGVKFDESEKTKE, from the internal region of the protein sequence according to NP_003290.1.
SpecificityRecognizes mouse TRA1. Species sequence homology: canine and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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