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You are here:Home » Antibodies » Abs to Heat Shock Proteins » Anti -GRP94 (Endoplasmin, 94kD Glucose-regulated Protein, GRP-94, Heat Shock Protein 90kD beta Member 1, Tumor Rejection Antigen 1, gp96 Homolog, HSP90B1, TRA1

Anti -GRP94 (Endoplasmin, 94kD Glucose-regulated Protein, GRP-94, Heat Shock Protein 90kD
beta Member 1, Tumor Rejection Antigen 1, gp96 Homolog, HSP90B1, TRA1

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
GRP94, also known as Heat shock protein 90kD beta, member 1 (HSP90B1), is an abundant resident endoplasmic reticulum (ER) lumenal stress protein which together with cytosolic Hsp90 belongs to the Hsp90 family of molecular chaperones. It plays an important role in maintaining protein homeostasis in the secretory pathway. Also, GRP94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. Recombinant human GRP94 protein, fused to His-tag at N-terminus.
Catalog #G3057-44G
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.01-0.03ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris buffered saline, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-KEGVKFDESEKTKE from an internal region of HSP90B1.
SpecificityRecognizes human HSP90B1. Species sequence homology: Canine, mouse, rat, zebrafish.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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