Anti -GLUT1 (Glucose Transporter 1, Solute Carrier Family 2, Facilitated Glucose
Transporter Member 1, Glucose Transporter Type 1, Erythrocyte/Brain, GLUT-1, HepG2 Glucose
Transporter, SLC2A1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E B |
|
| Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (Glut-1 to Glut-13, Mol. Wt. 40-80kD) and Sodium glucose co-transporter- 1 (SGLT-1, 662aa; ~75kD). Individual member of this family have identical predicted secondary structures with 12 transmembrane domains. Both N and c-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue- specific targeting. Glut isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. Glut-1 mediates glucose transport into red cells, and throughout the blood brain barrier, and supply glucose to most cells. | | | Catalog # | G3900-05B | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilutions | ELISA: 1:10,000-1:50,000. Control peptide can be used to coat plates at 1ug/ml | | Western Blot: 1:1000-1:5000 | | Optimal dilutions to be determined by the researcher. | | Control Peptide | G3900-05L: GLUT 1 (Glucose Transporter 1) Control Peptide | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a powder from PBS, 0.05% sodum azide. Reconstitute with 100ul sterile PBS. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to 15aa, near the C-terminal, cytoplasmic domain of human GLUT1, conjugated to KLH. Species Sequence Homology: porcine, bovine, rabbit, mouse and rat; 100%. | | Specificity | Recognizes human GLUT1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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