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You are here:Home » Antibodies » Abs to Glucose Transporters » Anti -GLUT 1 (Glucose Transporter 1)

Anti -GLUT 1 (Glucose Transporter 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-1 is detectable in many human tissues including those of the colon, lung, stomach, esophagus, and breast. GLUT-1 immunoreactivity in some cancers, including trans carcinoma of the urinary bladder, has been associated with aggressive behavior.
Catalog #G3900-12
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications have not been tested.
Recommended Dilutions
Western Blot: 5ug/ml, adipose and muscle tissue
Immunohistochemistry: 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.1, 0.1% sodium azide.
PurityPurified by affinity chromatography on a Sepharose 4B CNBr linked peptide column.
ImmunogenPeptide corresponding to 12aa, LFHPLGADSQV, of the C-terminus of human GLUT-1, conjugated to KLH.
SpecificityRecognizes human glucose transporter 1 from muscle and adipose tissue. Does not crossreact with GLUT-4. The MW of the glucose transporter precipitated by the serum is ~46kD.
Species CrossreactivityRat and mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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