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Anti -GLUT 2 (Glucose Transporter, Insulin Regulatable)
Anti -GLUT 2 (Glucose Transporter, Insulin Regulatable)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH IF |
|
| Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (GLUT 1 to GLUT 13, Mol. Wt. 40-80kD) and Sodium glucose co-transporter-1 (SGLT-1, 662aa; ~75kD). Individual members of this family have identical predicted secondary structures with 12 transmembrane domains. Both N- and C-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting. Glut isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. GLUT 2 provides glucose to the liver and pancreatic cells. | | | Catalog # | G3900-15M | | Applications | Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1000-1:10,000. G3900-15L Control peptide can be used to coat ELISA plates at 1ug/ml. | | Western Blot: 1-10ug/ml using ECL. This antibody identified a major band at about 53-61kD in various tissues (1). | | Immunohistochemistry: 2-10ug/ml. | | Optimal dilutions to be determined by the researcher. | | Recommended Control Peptide | G3900-15L: GLUT 2, Human Control Peptide | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | A 14aa synthetic peptide sequence near the C-terminal extracellular domain. (KLH). Species Sequence Homology: rat - 64%, mouse - 57%. | | Specificity | Recognizes human GLUT 2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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