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You are here:Home » Antibodies » Antibodies-Glucose Transporters » Anti -GLUT 3 (Glucose Transporter, Insulin Regulatable)

Anti -GLUT 3 (Glucose Transporter, Insulin Regulatable)


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Clone Host Grade Applications
Polyclonal Rabbit Serum E B
Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (GLUT 1 to GLUT 7, MW 40-60kD) and Sodium glucose co-transporter-1 (SGLT-1, 662aa; ~75kD). Individual members of this family have identical predicted secondary structures with 12 transmembrane domains. Both N- and C-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting.
GLUT isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. GLUT 1 mediates glucose transport into red cells, and throughout the blood brain barrier, and supply glucose to most cells. GLUT 2 provides glucose to the liver and pancreatic cells. GLUT 3 is the main transporter in neurons, whereas GLUT 4 is primarily expressed in muscle and adipose tissue and regulated by insulin.
Catalog #G3900-21
ApplicationsSuitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended DilutionWestern Blot: 1:1000-1:5000 (ECL)
ELISA: 1:10,0001:50,000, using 50100ng of antigen/well.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationNot Determined
FormSupplied as a liquid, 0.05% sodium azide
ImmunogenSynthetic peptide corresponding to the C-terminus, aa481-483 NSMQPVKETPGNA of mouse Glut-3 (KLH).
SpecificityRecognizes mouse Glut-3. Species Crossreactivity: rat. Does not recognize human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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