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Anti -GLUT 4 (Glucose Transporter 4, Glucose Transporter Type 4 Insulin-responsive, GLUT4, GLUT-4, Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 4, SLC2A4)
Anti -GLUT 4 (Glucose Transporter 4, Glucose Transporter Type 4 Insulin-responsive, GLUT4,
GLUT-4, Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 4, SLC2A4)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IH |
|
| GLUT4 is the insulin-regulated glucose transporter found in adipose tissue and striated muscle, responsible for glucose disposal. The stimulation of glucose uptake by insulin requires translocation of the GLUT4 glucose transporter from intracellular storage sites to the cell surface. Activation of phosphatidylinositol-3-OH kinase (PI3K) is required for this trafficking event, but it is not sufficient to produce GLUT4 translocation. Human insulin resistance involves a defect in GLUT4 traffic and targeting leading to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface. | | | Catalog # | G3900-50D | | Applications | Suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (Paraffin): 10-20ug/ml. Also suitable for use with frozen sections. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~5mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by affinity chromatography. | | Immunogen | A synthetic peptide corresponding to 12aa at the carboxyl terminus of the insulin regulatable glucose transporter conjugated to KLH. | | Specificity | Recognizes human glucose transporter 4. Species Crossreactivity: Mouse, Rat, Porcine and Monkey. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Glucose Transporter Insulin Regulatable, Glucose Transporter GLUT-4, kug |
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