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You are here:Home » Antibodies » Abs to Glucose Transporters » Anti -GLUT 12 (Glucose Transporter)

Anti -GLUT 12 (Glucose Transporter)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B
Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (GLUT-1 to GLUT-7, MW 40-60kD) and Sodium glucose co-transporter-1 (SGLT-1: 662aa, ~75kD). Individual members of this family have identical predicted secondary structures with 12 transmembrane domains. Both N- and C-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting. GLUT isoform differ in their tissue expression, substrate specificity and kinetic characteristics. GLUT-12 (human 617aa, monkey 621aa, ~ 50kD; ~30% homology with GLUT-4 and 40% with GLUT-10) is expressed in skeletal muscle, adipose tissue, and small intestine.
Catalog #G3900-97A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000-1:5000 (ECL).
ELISA: 1:10,000-1:50,000
Optimal dilutions to be determined by the researcher.
Recommended Control PeptideG3900-97: GLUT 12, Human, Control Peptide (Glucose Transporter)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in PBS, 0.05% sodium azide.
PuritySerum
ImmunogenSynthetic peptide consisting of 15aa sequence near the cytoplasmic, C-terminus of human Glut-12 (KLH). Species Sequence Homology
SpecificityRecognizes human GLUT 12. No significant sequence homology with other GLUTs.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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