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You are here:Home » Antibodies » Abs to Enzymes, Peroxidase » Anti -Glutathione Peroxidase 1

Anti -Glutathione Peroxidase 1

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Human glutathione peroxidase 1 (GPX1), a 22kD ubiquitously expressed selenium-dependent antioxidant enzyme and member of the glutathione peroxidase family, which catalyzes the glutathione-mediated reduction of toxic peroxides, protecting against oxidative damage and free radicals. Genetic polymorphisms resulting in variants of GPX1 have been linked with various cancers, including lung cancer, bladder cancer, and a significantly increased risk of developing breast cancer.
Catalog #G8127-04D
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 1-3 ug/ml. detects a band of approximately 22kD in human liver and kidney cell lysates.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.3, 0.02% sodium azide and 0.5% BSA.
PurityPurified by Immunoaffinity chromatography.
ImmunogenPeptide sequence C-REALPAPSDDATA corresponding to the internal region of glutathione peroxidase 1 (NP_000572.2).
SpecificityRecognizes isoform 1 of human glutathione peroxidase 1 (GPX1).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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