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You are here:Home » Antibodies » Abs to CD Markers » Anti -Glycophorin A (Glycophorin-A, MN Sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GYPA)

Anti -Glycophorin A (Glycophorin-A, MN Sialoglycoprotein, PAS-2, Sialoglycoprotein alpha,
CD235a, GYPA, GYPA)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Four main species of sialic acid-rich glycoproteins known as glycophorins A, B, C, and D have been characterized on human erythrocytes. These components carry blood group determinants and various receptors for lectins, bacteria, viruses, and parasites. Glycophorin A (GYPA) is a major sialoglycoprotein of the human erythrocyte membrane. It carries several medically important blood group antigens, M or N blood group antigen, which is determined byaa at residues 1 and 5. Glycophorin A spans the membrane with its amino terminus on the outside and its carboxyl terminus in the cytoplasm and has a molecular weight of 31kD The protein is specifically expressed on erythroid cell lineage. The gene encoding the glycophorin A protein maps to 4q28.2-q31.1 region of human chromosome and consists of 7 exons and has 97% sequence homology with glycophorin B.
Catalog #G8177-10A
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1:25-1:50
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Positive ControlTonsil
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11E208
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.05% sodium azide.
PuritySupernatant
ImmunogenFormalin fixed membrane from a hairy cell leukemia. Cellular Localization: Cell membrane.
SpecificityRecognizes human Glycophorin A.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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