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Anti -Glycophorin A (Glycophorin-A, MN Sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GYPA)
Anti -Glycophorin A (Glycophorin-A, MN Sialoglycoprotein, PAS-2, Sialoglycoprotein alpha,
CD235a, GYPA, GYPA)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
B IH |
|
| Four main species of sialic acid-rich glycoproteins known as glycophorins A, B, C, and D have been characterized on human erythrocytes. These components carry blood group determinants and various receptors for lectins, bacteria, viruses, and parasites. Glycophorin A (GYPA) is a major sialoglycoprotein of the human erythrocyte membrane. It carries several medically important blood group antigens, M or N blood group antigen, which is determined byaa at residues 1 and 5. Glycophorin A spans the membrane with its amino terminus on the outside and its carboxyl terminus in the cytoplasm and has a molecular weight of 31kD The protein is specifically expressed on erythroid cell lineage. The gene encoding the glycophorin A protein maps to 4q28.2-q31.1 region of human chromosome and consists of 7 exons and has 97% sequence homology with glycophorin B. | | | Catalog # | G8177-12G | | Applications | Suitable for use in Immunohistochemistry and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1-3ug/ml | | Immunohistochemistry (paraffin): 2-4ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human Liver lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-SVEIENPETSDQ, from the C-terminus of the protein sequence according to NP_002090. | | Specificity | Recognizes human Glycophorin A. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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